Liver functions changes in acute diarrhea in children

Diarrhea is considered to be one of the most common causes of morbidity and mortality among infants and children in developing countries. The present study was done to evaluate the incidence of hepatic affection or the occurrence of abnormal liver functions in infants and children presented with acute diarrhea with different degrees of dehydration. The study demonstrated that total number of patients with liver function impairment were [22.5% of cases]. All of them had elevated AST, either single elevation in 60% of cases with impaired liver function or combined AST and ALT elevation in 40% of cases with impaired liver function. The mean value of AST was 95 u /1 +/- 75.4, where mean value of ALT was 124 u/l +/- 8-5.8